The promising photosensitizing properties of hypericin, a substituted phenanthroperylene quinone naturally found in Saint John’s wort, has led to the proposal that it can be utilized in photodynamic therapy. Structurally modified derivatives are at the present time being investigated to… Read more ›
Due to an error in an analysis program, Fig. 4A in our Letter [1] was incorrectly plotted. The corrected graph is given herein. Edvin Erdtman ab, Daniel J.V.A. dos Santos c, Lennart Löfgren d, Leif A. Eriksson a* a Department… Read more ›
5-Aminolevulinic acid (5ALA) and ester derivates thereof are used as prodrugs in photodynamic therapy (PDT). The behavior of 5ALA and three esters of 5ALA in a DPPC lipid bilayer is investigated. In particular, the methyl ester displays a very different… Read more ›
Molecular dynamics simulations have been performed to explore the distribution and translocation of a set of furocoumarins (psoralen derivatives) inside saturated and partially unsaturated lipid membranes. Within the simulations, strong accumulation of the photodynamic drugs is observed near the polar… Read more ›