Closed projects

  1. Optimization of P-glycoprotein Modulators and Insights into the Efflux Mechanism (PTDC/QEQ-MED/0905/2012). PI: Prof. Maria J. U. Ferreira of iMed.UL/FFUL. Dr. Daniel dos Santos, participated as leader of the computational team and computational tasks.
  2. ​​Exploring a New Approach to Target KRAS Oncogene (EXPL/QEQ-MED/0502/2012). PI: Prof. Alexandra Paulo of iMed.UL/FFUL. Dr. Daniel dos Santos participated as Consultant for Molecular Modeling.
  3. New Drugs for Treating and Eradicating Malaria (HMSP-CT/SAU-ICT/0068/2009). PI: Dr. Maria Mota of IMM/FMUL. Dr. Daniel dos Santos participated as Molecular Modeling expert.
  4. ​Targeting the Mitochondrial Electron Transport Chain of Malaria Parasites: Computer-Assisted Design and Synthesis of bc1 Complex Inhibitors as Antimalarial Agents (​PTDC/SAU-FCT/098734/2008). PI: Prof. Rui Moreira of iMed.UL/FFUL. Dr Daniel dos Santos was the leader of two computational tasks and participated in another computational task.
  5. Diterpenes as Lead Compounds for Overcoming Multidrug Resistance in Cancer Cells: P-glycoprotein Modulators and Antiproliferative Agents (PTDC/QUI-QUI/099815/2008). PI: Prof. Maria J. U. Ferreira of iMed.UL/FFUL. Dr. Daniel dos Santos was the leader of three computational tasks.
  6. Exploiting the Type II Phosphomannose Isomerase BceAJ as a New Target for the Development of New Antimicrobials and for Biotechnological Applications (​PTDC/EBB-BIO/098352/2008). PI: Prof. Jorge H. Leitão IBB/IST. Dr. Daniel dos Santos participated in one computational task.