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Exploring the Molecular Basis of Qo bc1 Complex Inhibitors Activity to Find Novel Antimalarials Hits

Cytochrome bc1 complex is a crucial element in the mitochondrial respiratory chain, being indispensable for the survival of several species of Plasmodia that cause malaria and, Qo bc1 Complex Inhibitorstherefore, it is a promising target for antimalarial drug development. We Read more ›

Identification of new antimalarial leads by use of virtual screening against cytochrome bc1

Cytochrome bc1 is a validated drug target in malaria parasites. The spread of Plasmodium falciparum strains resistant to multiple antimalarials emphasizes the urgent need for new Identification of new antimalarial leads by use of virtual screening against cytochrome bc1drugs. We Read more ›