Synthesis, G-Quadruplex Stabilisation, Docking Studies, and Effect on Cancer Cells of Indolo[3,2-b]quinolines with One, Two, or Three Basic Side Chains
![Effect of Indolo[3,2-b]quinolines on Cancer Cells](https://i2.wp.com/chemistrybits.com/wp-content/uploads/2013/08/nfig004.gif?fit=220%2C198)
G-quadruplex (G4) DNA structures in telomeres and oncogenic promoter regions are potential targets for cancer therapy, and G4 ligands have been shown to modulate telomerase activity and oncogene transcription. Herein we report the synthesis and G4 thermal stabilisation effects, determined… Read more ›